Ovarian Cancer / Overview

Causes

A woman has a 1 in 67 chance of developing ovarian cancer. Ovarian cancer is the fifth most common cancer among women, and it causes more deaths than any other type of female reproductive cancer.

The cause is unknown.

The risk for developing ovarian cancer appears to be affected by several factors. The more children a woman has and the earlier in life she gives birth, the lower her risk of ovarian cancer. Certain genes (BRCA1 and BRCA2) are responsible for a small number of ovarian cancer cases. Women with a personal history of breast cancer or a family history of breast or ovarian cancer have an increased risk for ovarian cancer.

The use of fertility drugs may be associated with an increased chance of developing ovarian cancer, although this is a subject of ongoing debate.