Encyclopedia: TrkB
TrkB is the high affinity catalytic receptor for several "neurotrophins", which are small protein growth factors that induce the survival and differentiation of distinct cell populations. The neurotrophins that activate TrkB are: Brain Derived Neurotrophic Factor, or "BDNF", NT-4 , and NT-3 . As such, TrkB mediates the multiple effects of these neurotrophic factors, which includes neuronal differentiation and survival. The TrkB receptor is part of the large family of...
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