Definition
Sporotrichosis is a long-term ( chronic ) skin infection due to a certain fungus.
Symptoms
- Small, painless, red lump that develops at site of a recent injury (up to 3 months following injury).
- A progressive line of ulcers leading away from the initial ulcer.
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Symptoms
- Small, painless, red lump that develops at site of a recent injury (up to 3 months following injury).
- A progressive line of ulcers leading away from the initial ulcer.
Keep reading...
Causes
Sporotrichosis is caused by the fungus Sporothrix schenckii , which is found in vegetation. Infection commonly occurs when the skin is broken while handling plant materials such as rosebushes, briars, or mulch-rich dirt.
Sporotrichosis can be an occupational disease (for farmers, horticulturists, rose gardeners, plant nursery workers). Widespread (disseminated) sporotrichosis can develop in immunocompromised people when they inhale spore-laden dust.
Symptoms include a small, painless, red lump that develops at the site of infection and ultimately develops into an ulcer . Lesions are often on the hands and forearm, as these areas are a common site of injury.
The organism follows the lymph flow causing small ulcers to appear in lines on the skin as the infection progresses up the arm (or leg). These lesions do not heal unless treated and may remain ...
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Treatment
The skin infection is usually treated with potassium iodide (for example, SSKI) given by mouth 3 times per day or itraconazole by mouth. Treatment is prolonged and continues 1 month after the skin lesions clear. Systemic or disseminated infection is often treated with Amphotericin B, or sometimes itraconazole.
Possible Complications
In people with a normal immune system:
- Secondary skin infections
- Discomfort
In people who are immunosuppressed : - Disseminated disease
- Lung and breathing problems (such as pneumonia )
- Osteomyelitis
- Arthritis
- Meningitis
- Complications from medications -- amphotericin B can have extremely unpleasant side effects
Outlook (Prognosis)
With treatment, full recovery can be expected. Disseminated sporotrichosis is more difficult to treat and requires chemotherapeutic agents. Disseminated sporotrichosis can be life-threatening for immunocompromised people.
Prevention
Safer sex behavior can help prevent infection with HIV, the virus that causes AIDS. People with compromised immune systems should try to minimize exposure by taking measures like wearing thick gloves while gardening.
Exams and Tests
A physical examination reveals the typical lesions. A culture of biopsied tissue that demonstrates Sporothrix schenckii confirms the diagnosis.
