Rifamycin Overview

The rifamycins are a group of antibiotics which are synthesized either naturally by the bacterium Amycolatopsis mediterranei, or artificially. They are a subclass of the larger family, Ansamycin. Rifamycins are particularly effective against mycobacteria, and are therefore used to treat tuberculosis, leprosy, and mycobacterium avium complex infections. The rifamycin group includes the "classic" rifamycin drugs as well as the rifamycin derivatives Rifampicin, Rifabutin and Rifapentine. Streptomyces mediterranei was first isolated...

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