Protamine Overview

Encyclopedia: Protamine

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Protamines are small, arginine-rich, nuclear proteins that replace histones late in the haploid phase of spermatogenesis and are believed essential for sperm head condensation and DNA stabilization. When mixed with insulin, protamines slow down the onset and increase the duration of insulin action . Protamine sulfate is an antidote for heparin. Mice, humans, and certain fish have 2 or more different protamines, whereas the sperm of bull, boar, rat, rabbit,...


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Does anyone know the chemical structure of protamine sulfate?
A diagram would be helpful. Any related information on protamine sulfate and its impurities and...

I know that protamines are small, arginine-rich, nuclear proteins that replace histones late in the haploid phase of spermatogenesis and are believed essential for sperm head condensation and DNA stabilization,...

Asked by nascareer - 15 months ago

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  • Protamine - 9 replies

    Factors associated with increased risk of adverse reaction to protamine include (1) a history of fish allergy (2) exposure to protamine within the past two weeks (3) male infertility or vasectomy (4

    Dec 21, 2006

  • insuvet protamine - 2 replies

    Hi Im new to this so forgive me if you have been asked this before..My cat Buster has diabetis... and he is on Insuvet,he has 7 units once daily,and as the vial only lasts for 28days I...

    Oct 02, 2008

  • vasectomy and autoantibodies - 4 replies

    likely to have a reaction to protamine as the protamine cross-reacts with the anti-sperm Ab. are more likely to have a reaction to protamine as the protamine cross-reacts...

    Jul 02, 2007

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