Paraprotein Overview

Encyclopedia: Paraprotein

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A paraprotein is an abnormal protein in the urine or blood, most often associated with benign MGUS , where they remain "silent", and multiple myeloma. An excess in the blood is known as paraproteinemia. These are immunoglobulins or immunoglobulin light-chains that are produced by the clonal proliferation of plasma cells. Paraproteins form a narrow band, or 'spike' in protein electrophoresis as they are all exactly the same protein. Monoclonal free...


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More than one paraprotein band may be seen due to dimerization in IgA?
Is it true that more than one paraprotein band may be seen due to dimerisation...

Not that I have seen this assume clinical importance in my own practice, but if IgA monomers (singles if you will) are placed in a sample with IgA dimers (doubles),...

Asked by valer16 - 8 months ago

What is a paraprotein?
In reference to a multiple myeloma diagnosis.

paraprotein is an immunogloblin that is produced by a clone of neoplastic cells which are multupling at an abnormal rate(eg myeloma protien).

Asked by maltmix - 7 months ago


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