Oxaliplatin Overview

Encyclopedia: Oxaliplatin

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Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. It is typically administered in combination with fluorouracil and leucovorin in a combination known as FOLFOX for the treatment of colorectal cancer. Compared to cisplatin the two ammine groups are replaced by cyclohexyldiamine for improved antitumour activity. The chlorine ligands are replaced by the oxalato bidentate derived from oxalic acid in order to improve water solubility....


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oxaliplatin mechanism..how......?
is it similar to cisplatin mechanism?

Yes, but... probably more info than you wish to know Semin Oncol. 1998 Apr;25(2 Suppl 5):4-12 "Oxaliplatin, a platinum-based chemotherapeutic agent with a 1,2-diaminocyclohexane (DACH) carrier ligand, has shown in vitro and...

Asked by geena lee swee - 2 months ago

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  • oxaliplatin and 5FU - 11 replies

    as the treatment runs through his veins and as a result of the oxaliplatin, we have to be very careful that he I thought I would try to update and let you know how Tom is doing ok legs are a bit sore as...

    Sep 09, 2008

  • hiccups/oxaliplatin/xeloda - 2 replies

    Sam stared oxaliplatin and xeloda on Thursday and the hiccups began today. Not regular hiccups, big Sam stared oxaliplatin and xeloda on Thursday and the hiccups began today. Not regular hiccups...

    Jul 03, 2006

  • Gemcitabine and oxaliplatin (GEMOX) in patients with cisplatin-refractory... - 6 replies

    Gemcitabine and oxaliplatin (GEMOX) in patients with cisplatin-refractory germ cell tumors: a phase Combination chemotherapy with gemcitabine plus oxaliplatin in patients with intensively...

    Jun 15, 2008

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MedHelpMEDHELP

  • Tingling and numbness

    I will be recieving oxaliplatin and I have read that it always causes some toe and finger numbness. Does anyone know if t...

  • gemzar avastin cisplatin

    My mother has just began her third round of chemo since diagnosis over a year ago (October 96). This time she is doing ge...

  • adjuvant chemo

    Hello: I just had a colon resection for a stage 2a tumor in the large colon. Thank God they found nothing in the liver, l...


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Treatment Success for Oxaliplatin

DailyStrengthDAILYSTRENGTH


Condition Members Success
Colon Cancer 27 74%
Chemotherapy 0 74%
Head and Neck can... 1 100%
Depression - Teen... 1 100%

Overall, 87% (29 members) find Oxaliplatin helpful.