Neuromuscular Blocking Agents Overview

Encyclopedia: Neuromuscular-blocking Drugs

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Neuromuscular-blocking drugs block neuromuscular transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles. This is accomplished either by acting presynaptically via the inhibition of acetylcholine synthesis or release, or by acting postsynaptically at the acetylcholine receptor. While there are drugs that act presynaptically , the clinically-relevant drugs work postsynaptically. Clinically, neuromuscular block is used as an adjunct to anesthesia to induce paralysis, so that surgery, especially intra-abdominal...


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OmgiliOMGILI

  • neuromuscular blocking agents - 4 replies

    bear with me. I have access to get neuromuscular blocking agents (rocuronium, vecuronium, pancuronium in the past for anesthesiologists to CTB using IV barbiturates and neurologic blocking...

    Sep 23, 2008

  • Info on the PBT pills we took... - 10 replies

    should be observed in the administration of depolarizing neuromuscular blocking agents (e.g. by previously administered pyridostigmine bromide. Doses of non-depolarizing neuromuscular blocking

    Mar 16, 2006

  • colonblow - 4 replies

    of mEq. NOT SAFE. Interactions of this drug is, potentiates NEUROmuscular blocking... repost? colonblow Who's gonna be the first to try it?

    Jul 15, 2004


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