Membranous Nephropathy Overview

Membranous nephropathy is an immunologic renal disorder characterized by subepithelial immune deposits in the glomerular capillary wall. The subepithelial deposits are antigen-antibody complexes. They are formed by antibodies against cationic antigens crossing the anionic glomerular barrier or by circulating antigens. Although primary membranous predominantly has subepithelial deposits, secondary membranous may be characterized by subendothelial deposits and mesangial deposits. Rheumatoid arthritis itself can be associated with secondary MN. Drugs associated with...

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