Encyclopedia: Macroangiopathy
In macroangiopathy, fat and blood clots build up in the large blood vessels, stick to the vessel walls, and block the flow of blood. The decrease of blood flow through stenosis or clot formation impair the flow of oxygen to cells and biological tissues and lead to their death . Thus, tissues which are very sensitive to oxygen levels, such as the retina, develop microangiopathy and may cause blindness ....