Leuprolide Overview

Leuprorelin or leuprolide acetate is a gonadotropin-releasing hormone agonist . Proper Sequence: p-Glu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt By causing constant stimulation of the pituitary GnRH receptors, it initially causes stimulation , but thereafter decreases pituitary secretion of gonadotropins luteinizing hormone and follicle-stimulating hormone . Like other GnRH agonists, leuprolide may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, estrogen-dependent conditions , to treat precocious puberty, and to...