Leflunomide Overview

Precautions

Before taking leflunomide,

tell your doctor and pharmacist if you are allergic to leflunomide or any other drugs.

tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially cholestyramine (Cholybar, Questran), colestipol (Colestid), felbamate (Felbatol), mercaptopurine (Purinethol), rifampin (Rifadin, Rimactane, Rifater), methotrexate (Rheumatrex), tolbutamide (Orinase), troglitazone (Rezulin), and vitamins.

tell your doctor if you have or have ever had liver or kidney disease, hepatitis, severe infections, or conditions affecting the bone marrow or the immune system (including human immunodeficiency virus [HIV] and acquired immunodeficiency syndrome [AIDS]).

tell your doctor if you are breast-feeding.

if you are planning to father a child, you should talk to your doctor about stopping leflunomide prior to conception.