Irinotecan Overview

Encyclopedia: Irinotecan

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Irinotecan is a chemotherapy agent that is a topoisomerase 1 inhibitor. Chemically, it is a semisynthetic analogue of the natural alkaloid camptothecin. Its main use is in colon cancer, particularly in combination with other chemotherapy agents. This includes the regimen FOLFIRI which consists of infusional 5-fluorouracil, leucovorin, and irinotecan. Irinotecan was first introduced in Japan by the Pharmaceutical arm of Yakult Honsha as Campto. In 1994, it received accelerated FDA...


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  • Treating Cancer -- With Herbs - 19 replies

    from periwinkle plants. The anti-cancer drugs topotecan and irinotecan come from a component of the Chinese Treating Cancer -- With Herbs Many of the chemotherapies used to fight cancer in modern medicine...

    Mar 21, 2008

  • What does late stage look like? - 5 replies

    Hi all, my brother will soon begin Avastin/Irinotecan for liver and lung metastases from his colon Hi all, my brother will soon begin Avastin/Irinotecan for liver and lung metastases from his...

    Jun 12, 2008

  • Erbitux Not Statsig for Survival in CRYSTAL Study - 3 replies

    Phase 3 CRYSTAL study of ERBITUX (cetuximab) plus FOLFIRI, an irinotecan-based chemotherapy , the 1,198-patient CRYSTAL (Cetuximab combined with iRinotecan in first line therapY for metaSTatic

    Sep 16, 2008

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Treatment Success for Oxaliplatin

DailyStrengthDAILYSTRENGTH

Oxaliplatin is a popular treatment for Irinotecan.


Condition Members Success
Colon Cancer 27 74%
Chemotherapy 0 74%
Head and Neck can... 1 100%
Depression - Teen... 1 100%

Overall, 87% (29 members) find Oxaliplatin helpful.