Hereditary Pancreatitis Overview

Encyclopedia: Hereditary Pancreatitis

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Hereditary Pancreatitis is a genetic disease affecting enzyme production in the pancreas. In the pancreas, a genetic mutation causes the enzyme cationin trypsinogen to be made in a way which renders it resistant to inactivation through autolysis. Normally this autolysis mechanism prevents trypsinogen from being activated within the pancreas. However, when the abnormal trypsinogen is activated, it causes a chain reaction where all the trypsinogen in the pancreas is activated,...


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what is the main cause of pancreatitis?
Is it really a life threatening case? One of my friend died because of this...

It is not hereditary. Alcohol abuse is known to cause it as it over use of prescription drugs.

Asked by zambo - 360 days ago

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  • (untitled) - 19 replies

    Fibrosis, chronic and hereditary pancreatitis, alpha-1-antitrypsin, and other severe pulmonary diseases with Chronic and Hereditary Pancreatitis. Ambry Genetics' most recent developments focus on diagnosis

    Sep 12, 2006

  • Elevated lft's since june - 2 replies

    what else this could be? I have hereditary pancreatitis, but my amylase and lipase were fine. I am I hate to bother you with another ?, but I have looked everywhere and cannot find an answer...

    Oct 13, 2008

  • New here with no diagnosis yet. Help? - 3 replies

    of cancer. I am 38 year old female, I have had acute recurring hereditary pancreatitis since 1989. 2 years ago, my pancreatitis got a lot worse, so I started going to different doctors to find out why

    Nov 03, 2008

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