Hereditary Nonpolyposis Colorectal Cancer Overview

Hereditary nonpolyposis colorectal cancer , also known as Lynch syndrome, is characterised by a risk of colorectal cancer and other cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. HNPCC is subdivided into Lynch Syndrome I and Lynch Syndrome II . The increased risk for these cancers is due to inherited mutations that degrade the self-repair capability of DNA. Lynch syndrome was named...