Familial Hypercholesterolemia Overview

Encyclopedia: Familial Hypercholesterolemia

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Familial hypercholesterolemia is a genetic disorder characterized by high cholesterol levels, specifically very high low-density lipoprotein levels, in the blood and early cardiovascular disease. Many patients have mutations in the LDLR gene that encodes the LDL receptor protein, which normally removes LDL from the circulation, or apolipoprotein B , which is the part of LDL that binds with the receptor; mutations in other genes are rare. Patients who have one...


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familial hypercholesterolemia?
Just want some advice on familial hypercholesterolemia. I believe I have this condition as...

You ask a good question. The short answer is that you should discuss this more with your local doctor. My understanding is that at least 75% of your cholesterol is determined...

Asked by michelle - 22 months ago

what is meant by internalization-defective form of the Familial hypercholesterolemia receptor?
need help? please explain and list sources if possible. thanks.

This is a great question about the classic Nobel-prizewinning work of Brown and Goldstein in the 1970s at UT Southwestern. What they discovered was that a key regulator of...

Asked by fall - 9 months ago

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  • Familial HyperCholesterolemia - 2 replies

    Familial HyperCholesterolemia is very rare and I believe it starts at about 8... . My guess is that your family has a tendency towards higher cholesterol numbers, not...

    Nov 18, 2002

  • Statins for children? - 2 replies

    on children with Familial hypercholesterolemia or other genetic disorders to prevent early I saw on the news today that statins have been cleared for use on children. While I endorse...

    Jul 07, 2008

  • A Fallen Comrad - 9 replies

    hypercholesterolemia" http://en.wikipedia.org/wiki/Familial_hypercholesterolemia He passed away last week when of the hearts of every person he knew. He suffered from a condition called "Familial

    May 03, 2008

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  • Pure Hypercholesterolemia

    I recently went online and looked at my medical records that are available through my health insurance company. I notice...

  • Familial Hypercholesterolemia

    Hello, We are a group of high school students researching familial hypercholesterolemia for a genetic counselor project....

  • "pinch" behind left breast

    I am feeling a mild "pinch" feeling behind my left breast. 50 year old female - not menopausal yet - hypertension and hyp...

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