Factor Ix Overview

Encyclopedia: Factor Ix

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Factor IX is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B. It was discovered after a young boy named Stephen Christmas was found to be lacking this exact factor, leading to hemophilia, in 1952. Factor IX is inactive unless activated by factor XIa or factor VIIa . When activated into factor IXa, it acts by hydrolysing...

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Please see the webpages for more details on Hemophilia A and Hemophilia B.

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