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Cymbalta (Duloxetine)
A pharmacist explains how Cymbalta works, why doctors prescribe this antidepressant, and common side effects of the drug.
Duloxetine is used to treat depression and generalized anxiety disorder (GAD; excessive worry and tension that disrupts daily life and lasts for 6 months or longer). Duloxetine is also used to treat pain and tingling caused by diabetic neuropathy (damage to nerves that can develop in people who have diabetes). Duloxetine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). It works by increasing the amounts of serotonin and norepinephrine, natural substances in the brain that help maintain mental balance and stop the movement of pain signals in the brain.
A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants ('mood elevators') such as duloxetine during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do ...
Duloxetine is used to treat depression and generalized anxiety disorder (GAD; excessive worry and tension that disrupts daily life and lasts for 6 months or longer). Duloxetine is also used to treat pain and tingling caused by diabetic neuropathy (damage to nerves that can develop in people who have diabetes). Duloxetine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). It works by increasing the amounts of serotonin and norepinephrine, natural substances in the brain that help maintain mental balance and stop the movement of pain signals in the brain.
A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants ('mood elevators') such as duloxetine during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. However, experts are not sure about how great this risk is and how much it should be considered in deciding whether a child or teenager should take an antidepressant. Children younger than 18 years of age should not normally take duloxetine, but in some cases, a doctor may decide that duloxetine is the best medication to treat a child's condition.
Duloxetine comes as a delayed release (long-acting) capsule to take by mouth. When duloxetine is used to treat depression, it is usually taken once or twice a day with or without food. When duloxetine is used to treat generalized anxiety disorder or the pain of diabetic neuropathy, it is usually taken once a day with or without food. Take duloxetine at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take duloxetine exactly as directed. Do not take more or less of it, take it more often, or take it for a longer time than prescribed by your doctor. Swallow the capsules whole; do not split, chew, ...
Keep all appointments with your doctor. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
Duloxetine is also sometimes used to treat stress urinary incontinence (leakage of urine during physical activity such as coughing, sneezing, laughing, and exercise) in women. Talk to your doctor about using this medication to treat your condition. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911. Symptoms of overdose may include: agitation hallucinating (seeing things or hearing voices that do not exist) fast heartbeat fever
Before taking duloxetine, tell your doctor and pharmacist if you are allergic to duloxetine or any other medications. tell your doctor if you are taking thioridazine or a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or if you have stopped taking an MAO inhibitor within the past 14 days. Your doctor will probably tell you not to take duloxetine. If you stop taking duloxetine, you should wait at least 5 days before you start to take an MAO inhibitor. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as ...
Duloxetine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: nausea vomiting constipation diarrhea heartburn stomach pain
Unless your doctor tells you otherwise, continue your normal diet.
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
Duloxetine is a serotonin-norepinephrine reuptake inhibitor used for major depressive disorder , generalized anxiety disorder , pain related to diabetic neuropathy and in some countries for stress urinary incontinence . It is manufactured and marketed by Eli Lilly. Large number of side effects occurring during duloxetine treatment and lack of clear advantage over existing medications prompted critical reviews concluding that duloxetine "should not be used" for stress urinary incontinence and...
Duloxetine was created by Lilly researchers. David Robertson, David Wong, a co- discoverer of fluoxetine , and Joseph Krushinski are listed as inventors on ...
Learn about the prescription medication Cymbalta (Duloxetine Hcl), drug uses, dosage, side effects, drug interactions, warnings, and patient labeling.
Read about Cymbalta (duloxetine), the drug used to treat depression and also relieve peripheral neuropathic pain.
Jul 11, 2007 ... Read about Cymbalta (duloxetine), a drug prescribed for neuropathic pain associated with diabetic peripheral neuropathy, depression, ...
Drug information and side-effects for Cymbalta (duloxetine)
What are the side affects for the following drugs for nerve pain from adult type 2 Diabetes? Lyrica (Pregablin) Cymbalt...
Is there any way to alleviate the symptoms of duloxetine withdrawal? How long do symptoms usually last, and will they go ...
I am a 47 year old female who three years ago herniated a disc at the T1-T2 level which was deforming the spinal cord. I...
Novel action antidepressants include Serzone (nefazadone), Effexor (venlafaxine), Wellbutrin (buproprion), Desyrel (trazadone), Cymbalta (duloxetine) and Remeron (mirtazapine). The newest is Cymbalta, which gives similar results to tricyclics and operates on ...
The newer antidepressants are better tolerated by people with heart disease. These include bupropion (Wellbutrin, Wellbutrin SR and Wellbutrin XL), citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac and Prozac ...
You should NOT take Cymbalta if: You are allergic to duloxetine hydrochloride or other ingredients in Cymbalta. You currently or have recently taken a monoamine oxidase inhibitor (MAOI). You have ...
I did a quick wikipedia search, and it sounds like when Duloxetine was put into circulation it had unexpected and severe side-effects on lots of people. Although it had been...
Asked by Kitty_Cat - 5 months ago
It is a highly dependent anti-depressant. Has your gp given you anything else to help you come off it? I would go back and tell him whats happen and if...
Asked by HANNAH B - 5 months ago
A pharmacist explains how Cymbalta works, why doctors prescribe this antidepressant, and common side effects of the drug.
For those with diabetes testing your blood sugar is an important part of managing your health. Whether you're a pro or just starting out this slide show from the Mayo Clinic takes you through the entire process from washing your hands to recording the numbers to storing your glucometer.
This is an interesting paper since the manufactures (Elli Lilly) are clear about the antialgic...
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Full Text Duloxetine and Venlafaxine-XR in the Treatment of Major Depressive Disorder: A Meta-Analysis... Vis et al. Ann Pharmacother. 2005; 39: 1798-1807
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