Donepezil Overview

Encyclopedia: Donepezil

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Donepezil, marketed under the trade name Aricept , is a centrally acting reversible acetylcholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine. It has an oral bioavailability of 100% and easily crosses the blood-brain barrier. Because it has a half life of about 70 hours, it can be taken once a day. Initial dose is 5 mg per...


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Alzheimers Disease

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The brains of people with Alzheimer disease (AD exhibit two significantly defferent structures: amyloid plaques and neurofibrillary tangles. Both the plaques and tangles consist mostly of protein and are thought to interfere with brain function and contribute to the dementia that is a hallmark of AD.

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  • Aricept (donepezil) - 2 replies

    Has anyone used Aricept (donepezil) for HPPD? I know That Doctors experienced with HPPD have Has anyone used Aricept (donepezil) for HPPD? I know That Doctors experienced with HPPD have...

    Mar 05, 2007

  • Chicago: Studies Probe Diminishing Placebo Decline - 3 replies

    a poster yesterday showing that placebo patients in AD trials of donepezil initiated between 1995 and 1999 have declined more slowly than placebo groups of earlier (1990-1994) donepezil trials

    Aug 31, 2008

  • AcetylCholine Agonists. - 13 replies

    ) Huperzine A. Donepezil I found out on erowid named Donepezil, an alzheimer-medication. Check this out too:...

    Aug 15, 2008

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  • jANE

    COULD ARISEPT CAUSE A PULMINARY EMBOLISM?

  • Aricept Use and Effects

    My husband has been taking Aricept for dymentia for 1 year (he is in his late 50's), and his eyes are deteriorating. We ...

  • Unusually severe bilateral leg muscle cramping

    In the past month, I've had 3 episodes of incredibly severe bilateral muscle cramping in the calves, thighs, and buttoc...

Question and Answer

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Is there a drug you can take to improve intelligence?
I have heard of Donepezil but don't know much about it.

there is no drug or other substance to intake physically that will increase intelligence/intellect

Asked by Michael B - 5 months ago


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    ARICEPT? (donepezil hydrochloride) is a reversible inhibitor of the enzyme acetylcholinesterase, known chemically as...


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    ARICEPT? (donepezil hydrochloride) is a reversible inhibitor of the enzyme acetylcholinesterase, known chemically as...



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    PDF Lack of Pharmacokinetic or Pharmacodynamic Interaction Between Memantine and Donepezil Periclou et al. Ann Pharmacother. 2004; 38: 1389-1394

    www.theannals.com


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    Donepezil - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

    www.tkqlhce.com


Alzheimer's Self-Assessment

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How can you tell if you or loved one are falling prey to Alzheimer's disease? Take this quiz to help you determine if you need to seek the help of a medical professional.

Alzheimer's Self-Assessment