Dehydroepiandrosterone is a natural steroid prohormone produced from cholesterol by the adrenal glands, the gonads, adipose tissue, brain and in the skin . DHEA is the precursor of androstenedione, which can undergo further conversion to produce the androgen testosterone and the estrogens estrone and estradiol. DHEA is also a potent sigma-1 agonist. Synonyms for Dehydroepiandrosterone are: Dehydroisoandrosterone; 3-Hydroxy-5-androsten-17-one; 3-Hydroxyandrost-5-en-17-one; Dehydroisoandrosterone; Hydroxyandrost-5-en-17-one; Prasterone; trans-Dehydroandrosterone. Brand names for DHEA include Prastera, Fidelin...