Cardiotoxicity Overview

Encyclopedia: Cardiotoxicity

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Cardiotoxicity is the occurrence of heart muscle damage. The heart becomes weaker and is not as efficient in pumping and therefore circulating blood. Cardiotoxicity may be caused by chemotherapy treatment, complications from anorexia nervosa, or an incorrectly administered drug such as Bupivacaine. , Batrachotoxin , Heart failure , Chemocare.com:


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What's the market size of products/services for preclinical cardiotoxicity screening of pharmaceutical drugs?
hERG, other ion channels, zebrafish embryos, cardiomyocytes, etc. I am most interested in hERG...

Every drug has to undergo testing for hERG block and electrophysiological effects. The market is huge.

Asked by Don Paul K - 13 months ago

cocaine cardiotoxicity?
do you how cocaine causes cardiotoxicity directly as well as indirectly?

Interesting abstract above. That's direct for you. Indirectly, cocaine is a vasoconstrictor, and will cause the coronary arteries to clamp down, shutting off blood flow to the heart...

Asked by FACAS L - 8 months ago

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  • METHADONE AND CARDIOTOXICITY~~~~BEWARE~~~~BASED ON MEDICAL AND SCIENTIFIC... - 18 replies

    Judged: 1 1 Mechanisms of Opioid Associated Death and the Apparent Cardiotoxity of Methadone at Low be cardiotoxic, especially during the initial phase of treatment, and this may contribute

    Sep 20, 2008

  • Toxicology - 5 replies

    Toxicants in Plants (641 kb Dermal (934 kb Nephrotoxic Plants (227 kb Plants causing Cardiotoxicity Toxicology Industrial Toxicants (1.54 MB) Mycotoxins (2.60 MB Biotoxins (227 kb Feed and Water...

    Mar 17, 2008

  • Another 'Smart' Cancer Drug Can Have Toxic Effects on the... - 2 replies

    cardiologists, the study reviews research on the cardiotoxicity of 29 anti-cancer drugs as well as 30 years of experience at M. D. Anderson. Cardiotoxicity can occur in any patient. Generally speaking, patients

    Jan 27, 2008

Doctor-moderated Forums

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  • Herceptin

    How much information is there concerning heart problems with the use of Herceptin. I have also had adrimyicin? If you get...

  • Non-cardiotoxic ADD medication

    I have a patient who has ventricular tachycardia. She also suffers from ADD and my question is" what drug is useful to tr...

  • IIB Triple Negative Occult Cancer with CHF

    My 56 y.o. Caucasian mother was diagnosed in February...after bilateral radical mastectomy, they cannot find the tumor in...


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Treatment Success for Herceptin

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Herceptin is a popular treatment for Cardiotoxicity.


Condition Members Success
Breast Cancer 20 90%
Depression - Teen... 1 100%

Overall, 95% (21 members) find Herceptin helpful.