Encyclopedia: Bosentan
Bosentan is a dual endothelin receptor antagonist important in the treatment of pulmonary artery hypertension . It is licensed in the United States, the European Union and other countries by Actelion Pharmaceuticals for the management of PAH under the trade name Tracleer. Bosentan is a competitive antagonist of endothelin-1 at the endothelin-A and endothelin-B receptors. When endothelin-1 binds to these receptors, pulmonary artery pressure is elevated. By blocking this interaction,...
FAQs
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What medications are the most commonly used for treatment?
Currently, 5 drugs are specifically approved by the US Food and Drug Administration specifically for the treatment of PAH. They include (alphabetically): ambrisentan, bosentan, epoprostenol sodium, iloprost, sildenafil and treprostinil. ...
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What drug(s) may interact with ?
bosentan cilostazol cisapride cyclosporine dofetilide doxercalciferol certain medicines for anxiety or difficulty sleeping medicines for diabetes that are taken by mouth medicines for high cholesterol such as atorvastatin, fluvastatin, lovastatin, ...
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What drug(s) may interact with levonorgestrel in this emergency contraceptive...
The following medications could potentially make the Plan-B kit plan b morning after pill or the " day after pill " less effective at preventing pregnancy: antibiotics or medicines for ...
Question and Answer
My 5 year old has been diagnosed with Primary Pulmonary Hypertension, he has two heart...
teen health source help u
Asked by mum to an angel - 3 months ago
First at all, I apoligize for my mistakes in English. I have a sister who...
First of all, the responder above me is correct only in the case of secondary PAH. In the case of Primary PAH, there is no underlying cause that can be...
Asked by josemix1970 - 27 months ago
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