Apolipoprotein E is an apoprotein found in the chylomicron that binds to a specific receptor on liver cells and peripheral cells. APOE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. APOE was initially recognized for its importance in lipoprotein metabolism and cardiovascular disease. More recently, it has been studied for its role in several biological processes not directly related to lipoprotein transport, including Alzheimer's disease , immunoregulation, and...
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