Antigenic Variation Overview

Encyclopedia: Antigenic Variation

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Antigenic variation is the process by which an infectious organism alters its surface proteins in order to evade a host immune response. This change in antigenic profile may occur as the pathogen passes through a host population or may take place in the originally infected host. The strategy is particularly important for organisms that target long-lived hosts, repeatedly infect a single host, and are easily transmitted. Pathogens that express these...


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What are the kep points about the 'biological significance' & 'molecular basis' of antigenic variation?...
I have been asked to write an essay on the biological significance and molecular basis...

The neat thing about organisms like T. brucei (and other related parasites) is that they have "antigenic variation" (they can change the way their outermost proteins look). If the antigen...

Asked by Matthew S - 13 months ago

Is Antigenic variation considered a virulence factor?
In particular to Neisseria sp

I would say yes. Here is the definition of virulence from Dorland's: virulence [vir u lence](vir u-l ns)[L. virulentia, from virus poison] the degree of pathogenicity of a...

Asked by cali99boy - 19 months ago

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    Antigenic Variation: Molecular and Genetic Mechanisms of Relapsing Disease

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    Antigenic Variation Craig, Alister Scherf, Artur The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms 'shift shape', by genetic rearrangement...

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