Aminoglycosides Overview

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Aminoglycosides?
a. interfere with elongation of peptidoglycan b. are metabolic analogs of PABA and block folic acid...

Aminoglycosides work by binding to the bacterial 30S ribosomal subunit (some work by binding to the 50S subunit), inhibiting the translocation of the peptidyl-tRNA from the A-site to the P-site...

Asked by melly g - 10 months ago

Monitor for "casts" in urine for aminoglycosides?
What are casts and how to monitor for this in urine for a patient on...

Casts in urine sediment are cylindrical protein structures signifying some sort of stasis within the kidney. Since aminoglycosides can be toxic to the kidney, (nephrotoxic), the presence of urinary casts...

Asked by summation - 21 months ago


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