Depression  & St. John's Wort

Depression may be described as feeling sad, blue, unhappy, miserable, or down in the dumps. Most of us feel this way at one time or another for short periods.

True clinical depression is a mood disorder in which feelings of sadness, loss, anger, or frustration interfere with everyday life for an extended period of time.

See also:

• Adolescent depression
• Depression in the elderly

Depression often runs in families. This may due to your genes (inherited), learned behavior, or both. Even if your genes make you more likely to develop depression, a stressful or unhappy life event usually triggers the onset of a depressive episode.

Depression may be brought on by:

• Alcohol or drug abuse
• Childhood events like abuse or neglect
• Chronic stress
• Death of a friend or relative
• Disappointment at home, work, or school (in teens, this may be breaking up with a boyfriend or girlfriend, failing a class, or parents divorcing)
• Drugs such as sedatives and high blood pressure medications
• Medical conditions such as hypothyroidism (underactive thyroid), cancer, or hepatitis
• Nutritional deficiencies (such as a lack of folate and omega-3 fatty acids)
• Overly negative thoughts about one's self and life, self blame, and ineffective social problem solving skills
• Prolonged pain or having a major illness
• Sleeping problems
• Social isolation (common in the elderly)