
Chlamydia

Definition
Chlamydia
is a sexually transmitted disease caused by the bacteria Chlamydia trachomatis
.

Causes
Chlamydia
infection is caused by the organism Chlamydia trachomatis
. It is the most common sexually transmitted disease
in the United States. Sexually active individuals and individuals with multiple partners are at highest risk.
Chlamydia
may be acquired jointly with gonorrhea and/or syphilis, so individuals with one sexually transmitted disease must be screened for other sexually transmitted diseases as well. Untreated chlamydia
can lead to pelvic infection and infertility.
In men, chlamydia
may produce symptoms similar to those of gonorrhea (discharge from penis
or rectum
, burning on urination or defecation), and can also cause epididymitis
and orchitis
. However, up to 25% of infected men
may have no symptoms.
Chlamydia (female)
: only approximately 30% of women
will have symptoms due to chlamydia -- hence screening sexually active women for chlamydia is necessary to diagnose and treat asymptomatic
women in order to decrease the risk of developing complications. Women who do have symptoms may note vaginal discharge
, burning on urination, or abdominal pain.
Untreated infection may lead to pelvic inflammatory disease (PID)
, which can cause scarring of the fallopian tubes and result
in infertility
. Tubal scarring also increases the likelihood of an ectopic pregnancy
(tubal pregnancy).
If a
women is infected with chlamydia while pregnant, the infection can cause premature labor and delivery. In addition, the infant may develop chlamydial conjunctivitis
(eye infection) and chlamydial pneumonia.

Symptoms
MALE
FEMALE

Exams and Tests
The diagnosis
of chlamydia infection involves sampling of the urethral discharge
in males or cervical
secretions in females. If an individual engages in anal sexual contact, samples from the rectum may also be needed. The sample is sent for a
fluorescent or monoclonal antibody
test, DNA probe test or cell culture
. Some of these tests may also be performed on urine samples.

Treatment
The mainstay of therapy for chlamydia
includes appropriate antibiotic treatment -- these include: tetracyclines, azithromycin or erythromycin. All sexual contacts should be screened for chlamydia
.
Sexual partners must be treated to prevent passing the infection
back and forth. There is no significant immunity
following the infection
and a person may become repeatedly infected.
A
follow-up evaluation may be done in 4 weeks to determine if the infection has been cured.